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Tolerance Data Serial NumberJuan Pablo Agee

Juan Pablo Agee González (born November 5, 1993) is an Uruguayan footballer who plays for El Tanque Sisley.

References

External links
Profile at BDFA

Category:1993 births
Category:Living people
Category:Sportspeople from Montevideo
Category:Uruguayan footballers
Category:Uruguayan expatriate footballers
Category:C.A. Cerro players
Category:El Tanque Sisley players
Category:Nueva Chicago footballers
Category:Uruguayan Primera División players
Category:Argentine Primera División players
Category:Primera B Nacional players
Category:Expatriate footballers in Argentina
Category:Association football midfieldersYB-1 regulates transforming growth factor-beta production and collagen expression in human dermal fibroblasts.
Y-box-binding protein-1 (YB-1) is a multifunctional RNA-binding protein involved in the post-transcriptional regulation of several genes. A previous study of the role of YB-1 in dermal fibroblasts demonstrated that YB-1 mediates the expression of the pro-fibrotic cytokine transforming growth factor (TGF)-beta. The goal of this study was to determine whether YB-1 regulates the expression of its own gene product. A new antisense oligonucleotide (YB-1AS) was used to inhibit the expression of YB-1 in human dermal fibroblasts. The results demonstrate that the expression of YB-1 in human dermal fibroblasts was independent of active TGF-beta signaling. YB-1 inhibition did not alter the production or secretion of TGF-beta. However, inhibition of YB-1 expression significantly reduced the expression of Col1a1 and Col3a1, the major fibroblast-specific collagen isoforms, in

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